Interaction of complement with Neisseria meningitidis and Neisseria gonorrhoeae
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منابع مشابه
Interaction of complement with Neisseria meningitidis and Neisseria gonorrhoeae.
The importance of the complement system in host defense against systemic infection caused by neisseriae is emphasized by a number of clinical observations documenting the importance of antibody-dependent, complement-mediated serum bactericidal activity in protection from systemic meningococcal disease (17) and the well-recognized association between the resistance of gonococci to complement-dep...
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A library of Tn916-generated, tetracycline-resistant (Tc) mutants of the group B Neisseri meningitidis strain NMB was screened by using monoclonal antibodies (MAbs) that recognize structural differences in neisserial lipooligosaccharide (LOS). The LOS of parental strain NMB had a relative molecular mass of 4.5 kDa, reacted with MAbs 3F11 and 6B4 but not with MAb 4C4 or 6E4, and contained a lact...
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Neisseria gonorrhoeae acetylates its cell wall peptidoglycan (PG) at the C-6 position on N-acetylmuramic acid. To understand the effects of PG acetylation on PG metabolism and release of PG fragments, we have made mutations in the genes responsible for PG acetylation. An insertion mutation in a putative PG acetylase gene (designated pacA) resulted in loss of PG acetylation as detected by a high...
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DNA probe hybridisation was used to examine the relation between the cryptic plasmid from Neisseria gonorrhoeae and plasmids carried by pharyngeal isolates of Neisseria meningitidis and Neisseria lactamica. The complete gonococcal cryptic plasmid and HinfI derived digestion fragments subcloned into Escherichia coli were used to probe Southern blots of plasmid extracts. Homology was found to a p...
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ژورنال
عنوان ژورنال: Clinical Microbiology Reviews
سال: 1989
ISSN: 0893-8512,1098-6618
DOI: 10.1128/cmr.2.suppl.s11